Stress in the city: Brain activity and biology behind mood disorders of urban residents

Being born and raised in a major urban area is associated with greater lifetime risk for anxiety and mood disorders. Until now, the biology for these associations had not been described. A new international study, which involved Douglas Mental Health University Institute researcher Jens Pruessner, is the first to show that two distinct brain regions that regulate emotion and stress are affected by city living. These findings, published in Nature may lead to strategies that improve the quality of life for city dwellers.

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