High levels of master heat shock protein linked to poor prognosis in breast cancer patients

Monday, October 31, 2011 - 23:30 in Health & Medicine

Scientists report that patients whose estrogen receptor (ER)-positive breast cancers have high levels of an ancient cellular survival factor experience poor outcomes -- including increased mortality. According to the American Cancer Society, approximately two-thirds of breast cancer patients have ER-positive tumors. HSF1 status may shed light not only on prognosis but also on how such patients might respond to specific therapies.

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