Drugs That Act On 'Fasting Signal' May Curb Insulin Resistance In Obese

Wednesday, March 11, 2009 - 09:42 in Health & Medicine

A molecular switch found in the fat tissue of obese mice is a critical factor in the development of insulin resistance, report scientists. Previously found to increase glucose production by the liver during fasting, the culprit -- a protein known as CREB -- is also activated in fat tissue of obese mice where it promotes insulin resistance.

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