Drugs that act on 'fasting signal' may curb insulin resistance in obese

A report in the March issue of Cell Metabolism, a Cell Press publication, has found that a signal known to play a role during fasting also switches on early in the fat tissue of obese mice as they progress toward type 2 diabetes. Moreover, treatments that block that "fasting signal" in fat prevent the animals' resistance to insulin, according to the researchers.

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