Bioelectrical signals turn stem cells' progeny cancerous; Newly discovered 'instructor cells' can deliver deadly directions

Tuesday, October 19, 2010 - 09:30 in Biology & Nature

Biologists have found that a change in membrane voltage in newly identified "instructor cells" can cause stem cells' descendants to trigger melanoma-like growth in pigment cells a considerable distance away. This metastatic transformation is due to changes in serotonin transport. Discovery of this novel bioelectric signal and cell type could help prevent and treat diseases like cancer and vitiligo as well as birth defects.

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