How amyloid beta reduces plasticity related to synaptic signaling

Monday, December 28, 2009 - 15:07 in Health & Medicine

The early stages of Alzheimer's disease are thought to occur at the synapse, since synapse loss is associated with memory dysfunction. Evidence suggests that amyloid beta (A?) plays an important role in early synaptic failure, but little has been understood about A?'s effect on the plasticity of dendritic spines.

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