How neuronal activity leads to Alzheimer's protein cleavage
Monday, October 20, 2008 - 03:14
in Biology & Nature
Amyloid precursor protein (APP), whose cleavage product, amyloid-b (Ab), builds up into fibrous plaques in the brains of Alzheimer's disease patients, jumps from one specialized membrane microdomain to another to be cleaved, report Sakurai et al in the Journal of Cell Biology.