How Neuronal Activity Leads To Alzheimer's Protein Cleavage

Wednesday, October 22, 2008 - 13:21 in Biology & Nature

Amyloid precursor protein, whose cleavage product, amyloid-b, builds up into fibrous plaques in the brains of Alzheimer's disease patients, jumps from one specialized membrane microdomain to another to be cleaved, according to a new report in the Journal of Cell Biology.

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