How neuronal activity leads to Alzheimer's protein cleavage
Monday, October 20, 2008 - 11:42
in Biology & Nature
Amyloid precursor protein (APP), whose cleavage product, amyloid-b (Ab), builds up into fibrous plaques in the brains of Alzheimer's disease patients, jumps from one specialized membrane microdomain to another to be cleaved, report Sakurai et al.