Loss of Key Protein Boosts Neuron Loss in ALS
Friday, March 4, 2011 - 14:00
in Health & Medicine
Amyotrophic lateral sclerosis, known as ALS or Lou Gehrig's disease, is a notorious neurodegenerative condition characterized by the progressive deterioration of brain and spinal cord neurons, resulting in the gradual but catastrophic loss of muscle control and ultimately, death. In a paper, published in the journal Nature Neuroscience, a team of scientists at the UCSD School of Medicine and colleagues describe the profound and pervasive role of a key protein in ALS pathology called TDP-43.