Loss of key protein boosts neuron loss in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis, known as ALS or Lou Gehrig's disease, is a notorious neurodegenerative condition characterized by the progressive deterioration of brain and spinal cord neurons, resulting in the gradual but catastrophic loss of muscle control and ultimately, death. Scientists can now describe the profound and pervasive role of a key protein in ALS pathology called TDP-43.

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