New nucleotide could revolutionize epigenetics

Genes alone cannot explain the vast differences in the complexity of life. Scientists have found that what makes a worm and a human so much different isn’t the amount of DNA they carry, which is about the same, but rather the dynamic regulation of those genes by nongenetic factors: epigenetics. New research at The Rockefeller University has now uncovered a novel system of epigenetic regulation, one that adds a new nucleotide to the mammalian DNA code.

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