Cancer in a single catastrophe: Chromosome crisis common in cancer causation

Cancer is most often considered to be the result of accumulation of mutations over time -- often over years. Researchers have found that in one in 40 cases, chromosomes explode in a single event, creating hundreds of fragments and many mutations. The new process is particularly common in bone cancers. Although the cause of the shattered chromosomes is not known, the team suggest possible mechanisms to be studied.

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