Defects in immune system enzyme may increase risk of autoimmune disorders

Thursday, June 17, 2010 - 11:40 in Health & Medicine

Scientists have found that rare variants in the gene coding an enzyme that controls the activity of a key immune cell occur more frequently in individuals with autoimmune disorders like rheumatoid arthritis and type 1 diabetes. Their report identifies a pathway that could be a therapeutic target and may present a model for future investigations of the role of rare gene variants in common disorders.

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