Of Yeast And Men: Unraveling The Molecular Mechanisms Of Friedreich's Ataxia
Thursday, July 9, 2009 - 12:21
in Biology & Nature
Scientists have created an experimental model that produces large-scale expansion of GAA repeats during DNA replication, which is the cause of Friedreich's Ataxia. With this model, the researchers are able to analyze GAA repeat expansions and then identify cellular proteins that thwarted normal replication and promoted the elongated sequence.