When leukaemia returns, gene that mediates response to key drug often mutated
Thursday, March 10, 2011 - 14:10
in Health & Medicine
Despite dramatically improved survival rates for childhood acute lymphoblastic leukaemia (ALL), relapse remains a leading cause of death from the disease. Work led by St. Jude Children's Research Hospital investigators identified mutations in a gene named CREBBP that may help the cancer resist steroid treatment and fuel ALL's return...