Half-dose flu shot appears to produce immune response in young, healthy adults

Individuals younger than 50 who have been previously vaccinated do not appear to have a substantially different immune response to a half-dose of influenza vaccine than to a full dose, according to a report in the December 8/22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. This suggests that half-dose vaccination in healthy young individuals may be effective in times of vaccine shortage.

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