Molecular engines star in new model of DNA repair
Wednesday, January 8, 2014 - 20:30
in Biology & Nature
A new model of DNA repair is revealed in a new study. In this model, RNA polymerase patrols tracks of double-stranded DNA and stalls over damaged areas. Our health depends in large part upon the ability of specialized enzymes to find and repair the constant barrage of DNA damage brought on by ultraviolet light radiation and other sources. In a new study NYU School of Medicine researchers reveal how an enzyme called RNA polymerase patrols the genome for DNA damage and helps recruit partners to repair it. The result: fewer mutations and consequently less cancer and other kinds of disease.