The Solution To A 50-year-old Riddle: Why Certain Cells Repel One Another
Saturday, October 3, 2015 - 14:10
in Biology & Nature
When cells from the connective tissue collide, they repel one another - this phenomenon was discovered more than 50 years ago. It is only now, however, that researchers at the University of Basel have discovered the molecular basis for this process, as they report in the journal Developmental Cell. Their findings could have important implications for cancer research. Fibroblasts are motile constituents of the connective tissue and also regulate its stiffness. Moreover, fibroblasts play an important role in malignant skin diseases such as melanoma. In research, they serve as a model system for studying cell migration. Signaling pathway identified read more