Neurons Rewrite Their DNA On The Go

Tuesday, April 28, 2015 - 00:00 in Biology & Nature

Scientists have discovered that neurons use minor "DNA surgeries" to toggle their activity levels all day, every day, and since these activity levels are important in learning, memory and brain disorders, it could shed light on a range of important questions.  "We used to think that once a cell reaches full maturation, its DNA is totally stable, including the molecular tags attached to it to control its genes and maintain the cell's identity," says Hongjun Song, Ph.D., a professor of neurology and neuroscience in the Johns Hopkins University School of Medicine's Institute for Cell Engineering. "This research shows that some cells actually alter their DNA all the time, just to perform everyday functions." read more

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