How Persistent Bacteria Avoid Antibiotics

Some bacteria achieve resistance to antibiotics through mutation but other types of bacteria, known as 'persistent' bacteria, are not resistant to the antibiotics but simply continue to exist in a dormant or inactive state while exposed to antibacterial treatment.  These bacteria later 'awaken' when that treatment is over, resuming their work.It was known that there is a connection between these kind of bacteria and the naturally occurring toxin HipA in the bacteria, but scientists did not know the cellular target of this toxin and how its activity triggers dormancy of the bacteria. read more

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