Pyridomycin: Nature's Natural Antibiotic Against Tuberculosis

Tuesday, December 3, 2013 - 12:10 in Health & Medicine

Modern science has made it possible to synthesize increasingly targeted drugs but Ma Nature is not out of it yet - it just took science to discover what nature could do. Pyridomycin, a substance produced by non-pathogenic soil bacteria, has been found to be a potent antibiotic against a related strain of bacteria that cause tuberculosis.  The Ecole Polytechnique Fédérale de Lausanne scientists who discovered this property now have a better understanding of how its complex, three-dimensional structure allows it to act simultaneously on two parts of a key enzyme in the tuberculosis bacillus, and in doing so, dramatically reduce the risk that the bacteria will develop multiple resistances.  read more

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