How the microenvironment can guide secretory cavities into tubes by mechanical forces
Tuesday, February 23, 2016 - 10:40
in Biology & Nature
The underlying mechanism revealed for the formation and growth of a fundamental type of tissue – epithelial tubes. Defects in the architecture of epithelial tubes lead to diseases such as cholestasis, atherosclerosis and polycystic kidney disease. The research findings contribute towards a deeper understanding of the principles that underline epithelial tube formation, and offer opportunities for developing better therapies for such diseases.