Genetic variant protects some Latina women from breast cancer

A genetic variant common in Latina women protects against breast cancer, an international research collaboration has found. The variant, a difference in just one of the three billion "letters" in the human genome known as a single-nucleotide polymorphism (SNP), originates from indigenous Americans and confers significant protection from breast cancer, particularly the more aggressive estrogen receptor-negative forms of the disease, which generally have a worse prognosis.

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