Long non-coding RNA prevents the death of maturing red blood cells

A long non-coding RNA prevents programmed cell death during one of the final stages of red blood cell differentiation, according to Whitehead Institute researchers. Preventing normal cell death is a key step in the development of leukemias and other cancers. Because of its role in red blood cell apoptosis, this lncRNA or the pathways through which it exerts its anti-apoptotic effects may represent potential therapeutic targets.

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