Scientists discover secret life of chromatin: DNA/histone combination, a destination for cell signals, also talks to other proteins

Chromatin -- the intertwined histone proteins and DNA that make up chromosomes -- constantly receives messages that pour in from a cell's intricate signaling networks: Turn that gene on. Stifle that one. But chromatin also talks back, scientists report, issuing orders affecting a protein that has nothing to do with chromatin's central role in gene transcription -- the first step in protein formation.

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