Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia

Scientists have used an unconventional approach to cancer drug discovery to identify a new potential treatment for acute myeloid leukemia (AML), an aggressive blood cancer that is currently incurable in 70 percent of patients. The researchers have pinpointed a protein called Brd4 as a novel drug target for AML. Using a drug compound that inhibits the activity of Brd4, the scientists were able to suppress the disease in experimental models.

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