The unfolding 'SAGA' of transcriptional co-activators
Thursday, July 14, 2011 - 21:30
in Health & Medicine
Successful gene expression requires the concerted action of a host of regulatory factors. Long overshadowed by bona fide transcription factors, co-activators -- the hangers-on that facilitate transcription by docking onto transcription factors or modifying chromatin -- have recently come to the fore.