Prostate cancer gets around hormone therapy by activating a survival cell signaling pathway
Tuesday, June 14, 2011 - 16:30
in Health & Medicine
Cancer is crafty. Researchers found that when a common type of prostate cancer was treated with conventional hormone ablation therapy blocking androgen production or androgen receptor (AR) function -- which drives growth of the tumor -- the cancer was able to adapt and compensate by activating a survival cell signaling pathway, effectively circumventing the roadblock put up by this treatment.