Mutations in single gene predict poor outcomes in adult leukemia; Discovery may guide treatment for acute myeloid leukemia

Decoding the DNA of a woman who died of acute myeloid leukemia (AML) has led researchers to a gene that they found to be commonly altered in many patients who died quickly of the disease. The findings, if confirmed in larger studies, suggest that a diagnostic test for mutations in the gene could identify AML patients who need more aggressive treatment right from the start.

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