Researchers discover fundamental step in immune-system development

Wednesday, March 24, 2010 - 16:28 in Health & Medicine

Researchers have discovered a fundamental step in the development of the immune system, one that allows B cells to mature and fight disease by producing effective antibodies. Immunologists have demonstrated that immature B cells in the bone marrow must receive a positive signal, mediated by the Erk protein, before they can migrate to the spleen where they mature and are activated.

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