Light shed on mechanism of action of 'date rape drug'

Scientists have discovered two new metabolic pathways by which products of lipid peroxidation and some drugs of abuse, known as 4-hydroxyacids, are metabolized. The pathways were identified by a combination of metabolomics and mass isotopomer analysis. The findings shed new light on the mechanism of action of the drug of abuse gamma-hydroxybutyrate, also known as "the date rape drug."

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