All Tied Up: Tethered Protein Provides Long-sought Answer

The tools of biochemistry have finally caught up with lactose repressor protein. US and Italian biologists this week offer new results about the oft-studied protein -- the first known genetic regulatory protein. Using cutting-edge techniques, the scientists tied together the arms of lactose repressor protein and then measured the protein's capacity to form looped DNA structures. The tests help gauge the importance of protein flexibility.

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