Novel Genetic Finding Offers New Avenue For Future Crohn's Disease Treatment

Researchers have identified a novel link between ITCH, a gene known to regulate inflammation in the body and NOD2, a gene which causes the majority of genetic Crohn's Disease diagnoses. ITCH, when malfunctioning, causes widespread inflammatory diseases, including inflammatory bowel disease, gastritis, uncontrolled skin inflammation, and pulmonary pneumonitis. Researchers found that ITCH also influences NOD2-induced inflammation.

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