Nervous System May Be Culprit In Deadly Muscle Disease

Long considered a "muscle" disorder, Pompe disease may have a previously unknown neural component. In mouse models of the disease, researchers have discovered that signals from the spinal cord are too weak to reach the diaphragm -- the muscle that controls breathing. The finding suggests that therapies to treat the disease will need to take the central nervous system into account in order to be fully effective.

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