Disrupting A Brain Protein Produces Antidepressant-like Effect In Mice

A brain protein involved in fear behavior and anxiety may represent a new target for depression therapies, according to new research. The study showed that disrupting the ASIC1a protein produced an antidepressant-like effect in mice. The effect was similar to that produced by currently available antidepressant drugs, but ASIC1a's effect appears to occur through a new and different biological mechanism.

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