Exhausted B Cells Hamper Immune Response To HIV

Recent studies have shown that HIV causes a vigorous and prolonged immune response that eventually leads to the exhaustion of key immune system cells -- CD4+ and CD8+ T-cells -- that target HIV. These tired cells become less able to fight the virus. Now, researchers have shown that a similar type of exhaustion strikes another important brigade of immune system soldiers: the B cells that make virus-fighting proteins called antibodies.

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