Tumor Suppressor Genes Speed Up And Slow Down Aging In Engineered Mouse

Friday, May 30, 2008 - 15:28 in Biology & Nature

Mayo Clinic researchers have developed an animal model that can test the function of two prominent tumor suppressor genes, p16 and p19, in the aging process. Scientists knew that both these genes were expressed at increased levels as humans and mice age, but their role in the aging process was not clear. Findings show that p16 provides gas to accelerate cellular aging, while p19 stops that process.

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