Recombination hotspot stacks the DNA deck in finding a new diabetes susceptibility gene
Thursday, November 4, 2010 - 08:40
in Biology & Nature
The autoimmune disease type 1 diabetes (T1D), also known as juvenile diabetes, is diagnosed in approximately 70,000 children worldwide per year. Genetics is increasingly being recognised as playing a significant role in susceptibility to the disorder, but outside a handful of genes, a clear understanding of the genetic architecture that underlies T1D has remained elusive. In a study published online today in Genome Research (www.genome.org), scientists have identified a novel gene associated with diabetes in mice that is revealing new clues about genomic mechanisms that could underlie T1D susceptibility...