Structure of protein complex that plays key role in modulating immune system revealed

Wednesday, January 20, 2016 - 13:32 in Biology & Nature

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have solved the atomic structure of a unique ubiquitin ligase complex. Ubiquitin is best known for its role in protein degradation, but more recently seen as important for cell signaling, DNA repair, anti-inflammatory, and immune responses.

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