MicroRNAs dictate the Epstein-Barr virus' elaborate waiting game, cancer formation

While most commonly associated with mononucleosis, Epstein-Barr virus (EBV) has been linked to many diseases that affect people long after the initial infection takes place, including some forms of cancer. In the current issue of the Journal of Biological Chemistry, scientists at The Wistar Institute describe how viral microRNA – small segments of RNA that suppress the effects of gene activity – allows EBV to hide within cells and evade the immune system. The scientists believe their findings may one day enable physicians to flush EBV out of hiding, allowing a healthy immune system to rid the body of the virus.

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