Breast cancer metastasis increases after estrogen and progestin hormone therapies, study finds

Thursday, May 6, 2010 - 12:51 in Health & Medicine

After menopause, 6 to 10 million women take hormone therapies, which are often a combination of estrogen and progestin, to replace hormones lost from inactive ovaries. Progestin is a hormone that is used to counteract the potentially negative effects of estrogen therapy on the uterus. In studies sponsored by the National Institutes of Health, evidence has been found that estrogen and progestin in hormone therapies increase the risk of breast cancer in post-menopausal women. Now, a University of Missouri study has found that progestins can also increase the chance of the cancer metastasizing, or spreading to the lymph nodes.

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