Copper-Free Click Chemistry Used in Mice

(PhysOrg.com) -- For the first time, the widely used molecular synthesis technique known as click chemistry has been safely applied to a living organism. A team of Berkeley Lab and UC Berkeley researchers has developed a unique copper-free version of click chemistry to create biomolecular probes for in vivo studies of live mice. Conventional click chemistry reactions require a copper catalyst that is toxic to cells and organisms.

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