Key step in the 'puncture' mechanism of cell death revealed

Monday, May 12, 2008 - 14:07 in Health & Medicine

A team of medical researchers led by Dr Ruth Kluck at Melbourne`s Walter and Eliza Hall Institute (WEHI) has discovered a key step in the mechanism by which cells destroy themselves. In this process, called “apoptosis”, certain proteins cause the cell to self-destruct by puncturing its “power plant.” How the proteins do this has been clarified by the WEHI team. The discovery is an important step towards the identification of targets for drugs designed to regulate cell death.

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