New Protein Players Found in Key Disease-Related Metabolic Pathway
Thursday, September 25, 2014 - 11:32
in Biology & Nature
Cells rely on the mechanistic target of rapamycin complex 1 (mTORC1) pathway--which senses the availability of nutrients--to coordinate their growth with existing environmental conditions. The lab of Whitehead Member David Sabatini has identified a family of proteins that negatively regulate the branch upstream of mTORC1 that senses amino acids, the building blocks of proteins.