To peer inside a living cell

Tuesday, October 6, 2009 - 03:14 in Physics & Chemistry

Electron microscopes are the most powerful type of microscope, capable of distinguishing even individual atoms. However, these microscopes cannot be used to image living cells because the electrons destroy the samples. Now, MIT assistant professor Mehmet Fatih Yanik and his student, William Putnam, propose a new scheme that can overcome this limitation by using a quantum mechanical measurement technique that allows electrons to sense objects remotely. Damage would be avoided because the electrons would never actually hit the imaged objects. Such a non-invasive electron microscope could shed light on fundamental questions about life and matter, allowing researchers to observe molecules inside a living cell without disturbing them. Yanik and Putnam report their new approach in the October issue of Physical Review A — Rapid Communications. If successful, such microscopes would surmount what Nobel laureate Dennis Gabor concluded in 1956 was the fundamental limitation of electron microscopy:...

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