Diverse 'connectomes' hint at genes' limits in the nervous system

Tuesday, February 10, 2009 - 09:57 in Biology & Nature

Genetics may play a surprisingly small role in determining the precise wiring of the mammalian nervous system, according to painstaking mapping of every neuron projecting to a small muscle mice use to move their ears. These first-ever mammalian "connectomes," or complete neural circuit diagrams, reveal that neural wiring can vary widely even in paired tissues on the left and right sides of the same animal.

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