Treatment of obstructive sleep apnea with CPAP may lower blood pressure
Treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) may also lower blood pressure among hypertensive adults, according to researchers in Spain, who will present his findings at the American Thoracic Society’s 2008 International Conference in Toronto on Sunday, May 18. The study included 394 consecutive patients with high blood pressure and non-sleepy OSA—those with mild enough OSA that their daytime alertness was unaffected. They were randomized to receive either CPAP or no treatment.
Blood pressure was measured at three-, six- and 12-month follow-ups after their baseline evaluation. The researchers found that, on average, patients who used the CPAP machine experienced an average 2mmHg drop in both systolic and diastolic blood pressure at the end of the year when compared to patients who did not use the CPAP machine.
“This is the largest study trial in the field and it shows hat CPAP has an effect on cardiovascular outcomes regardless of symptoms,” said Ferran E. Barbé, M.D., who headed the research. “This suggests that CPAP can not only be used to treat the symptoms of sleep apnea (daytime sleepiness), but also to reduce cardiovascular risk in apneic patients.”
The patients for whom the effect was most produced used the CPAP machine for more than five hours a night. “The mechanism by which CPAP is able to effect a drop in blood pressure is complex and it is mainly related to a reduction in sympathetic tone, oxidative stress,” explained Dr. Barbé.
Although researchers do not yet know whether CPAP should be recommended for all OSA patients with high blood pressure and without daytime sleepiness, barring contraindications, the results point to the need for further study of the cardiovascular benefits of CPAP in OSA patients.
“In the future, we would like to know the effects of CPAP treatment on other cardiovascular outcomes such as stroke, myocardial infarction or heart failure,” said Dr. Barbé.
Source: American Thoracic Society
- Low-income patients with obstructive sleep apnea are less likely to start CPAP therapyWed, 1 Apr 2009, 10:58:44 EDT
- Problem solving and coping styles related to CPAP adherenceMon, 8 Jun 2009, 1:56:54 EDT
- Less costly, more accessible and as effective: Simplified treatment for sleep apneaFri, 6 Mar 2009, 2:02:04 EST
- Study finds that combination therapy reduces pauses in breathing caused by OSAMon, 13 Jun 2011, 10:04:22 EDT
- Men who work with their female partners more likely to adhere to CPAP therapyMon, 8 Jun 2009, 1:56:57 EDT
Articles on the same topic
- Israeli study finds obstructive sleep apnea is health factor from day 1Wed, 21 May 2008, 7:35:31 EDT
- Study finds that obstructive sleep apnea causes earlier death in stroke patientsSun, 18 May 2008, 17:21:11 EDT
- People with obstructive sleep apnea at risk for cardiac stress on airline flightsSun, 18 May 2008, 8:21:40 EDT
- Green tea compounds beat OSA-related brain deficitsThu, 15 May 2008, 8:21:49 EDT
- Israeli study finds obstructive sleep apnea is health factor from day 1from PhysorgWed, 21 May 2008, 12:28:46 EDT
- Obstructive Sleep Apnea Is Health Factor From Day Onefrom Science DailyWed, 21 May 2008, 9:28:08 EDT
- Chemicals found in green tea beat OSA-related brain deficitsfrom Science CentricWed, 21 May 2008, 9:22:09 EDT
- Study finds that obstructive sleep apnea causes earlier death in stroke patientsfrom PhysorgMon, 19 May 2008, 3:56:06 EDT
- Obstructive Sleep Apnea Causes Earlier Death In Stroke Patients, Study Findsfrom Science DailySun, 18 May 2008, 19:14:06 EDT
- Treatment Of Obstructive Sleep Apnea With CPAP May Lower Blood Pressurefrom Science DailySun, 18 May 2008, 19:14:05 EDT
- People With Obstructive Sleep Apnea At Risk For Cardiac Stress On Airline Flightsfrom Science DailySun, 18 May 2008, 13:14:21 EDT
- Green Tea May Help With Sleep Apnea's Cognitive Defectsfrom Scientific BloggingThu, 15 May 2008, 12:35:35 EDT
- Green tea compounds beat OSA-related brain deficitsfrom PhysorgThu, 15 May 2008, 10:42:07 EDT
- Green tea compounds beat sleep apnea-related brain deficitsfrom Science BlogThu, 15 May 2008, 10:14:14 EDT
- Chemicals found in green tea beat OSA-related brain deficitsfrom Science CentricThu, 15 May 2008, 9:07:11 EDT
- Green Tea Compounds Beat Obstructive Sleep Apnea-related Brain Deficits, Study Showsfrom Science DailyThu, 15 May 2008, 8:21:14 EDT
Latest Science NewsletterGet the latest and most popular science news articles of the week in your Inbox! It's free!
Learn more about
Check out our next project, Biology.Net
From other science news sites
Popular science news articles
- Mars had oxygen-rich atmosphere 4,000 million years ago
- The contribution of particulate matter to forest decline
- Voices may not trigger brain's reward centers in children with autism, Stanford/Packard study shows
- Scientists find new source of versatility so 'floppy' proteins can get things done
- An environmentally friendly battery made from wood
- Even with defects, graphene is strongest material in the world
- Detection of the cosmic gamma ray horizon: Measures all the light in the universe since the Big Bang
- Genetic engineering alters mosquitoes' sense of smell
- Allosaurus fed more like a falcon than a crocodile, new study finds
- 'Popcorn' particle pathways promise better lithium-ion batteries