Mitochondria Mutation Linked To Human Parkinson's Disease For First Time
Thursday, April 2, 2015 - 14:20
in Health & Medicine
A new study using stem cells derived from patients who have Parkinson's disease (PD) has confirmed for the first time what scientists have long suspected - that the most common mutation linked to both sporadic and familial Parkinson's disease (PD) wreaks its havoc by altering the function of mitochondria in neurons that produce the neurotransmitter dopamine. Mitochondria are energy-producing organelles found in large numbers in most cells and are necessary for life. Zeng says the Park2 mutation altered mitochondrial structure and function in dopamine producing neurons, causing them to die. Dopamine is an essential neurotransmitter which regulates movement and emotion. read more