Counterintuitive: Anti-Inflammatory Protein May Trigger Alzheimer's Disease Plaque

Friday, January 23, 2015 - 10:30 in Health & Medicine

Inflammation has long a target in Alzheimer's disease studies so a new finding in Neuron is counterintuitive. In the study, researchers hace uncovered the mechanism by which anti-inflammatory processes may trigger the disease and this anti-inflammatory process might actually trigger the build-up of sticky clumps of protein that form plaques in the brain. These plaques block brain cells' ability to communicate and are a well-known characteristic of the illness. The finding suggests that Alzheimer's treatments might need to be tailored to patients depending on which forms of Apolipoprotein E, a major risk factor for Alzheimer's disease, these patients carry in their genes. read more

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